GETTING MY LDN-27219 PHARMACOLOGICAL PROPERTIES TO WORK

1 especially interesting compound is LDN-27219. Though most tTG inhibitors are meant to bind to your protein crosslinking active web-site, LDN-27219 as a substitute binds for the nucleotide binding pocket from the enzyme though it can be in its closed-state conformation, and stabilizes that conformation to circumvent crosslinking activity.78 Schnei